Manager, Bioinformaticist (R1089522) in Durham, NC at IQVIA™

Date Posted: 8/23/2019

Job Snapshot

  • Employee Type:
  • Location:
    Durham, NC
  • Job Type:
  • Experience:
    Not Specified
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Job Description

Q2 Solutions is a leading clinical trial laboratory services organization with end-to-end laboratory services and secure, enterprise-wide biospecimen and consent management solutions. With a relentless focus on quality and innovation, Q2 Solutions uses its global experience and scientific expertise to transform science and data into actionable medical insights that help customers improve human health.  A joint venture of IQVIA (formerly QuintilesIMS) and Quest Diagnostics, Q2 Solutions combines the best of each parent organization’s clinical trials laboratory services capabilities to fulfill its mission of treating each sample as if a life depends on it.


The EA Genomics business unit of Q2 Solutions is the global center of excellence in genomic testing and high-performance computation and bioinformatics methodology.

As a Bioinformaticist within the translational genomics department of EA Genomics, you will be responsible to provide advanced analytical and interpretive expertise of NGS data. You will be an integral member of a team that strives to continually develop novel algorithmic and pipeline solutions serving the scientific and bioinformatic analysis needs of our clients. You will present scientific findings internally and externally, author analytical reports and may present results at meetings and conferences.


  • Develop novel approaches to address complex problems in NGS data analysis including RNA-SEQ and DNA-SEQ applications. (e.g. circulating tumor DNA variant calling, immune-oncology, etc.)
  • Perform detailed and custom next generation sequencing analysis tasks such as data processing and visualization.
  • Identify best-in-class methods, software solutions and strategies for bioinformatic applications. This includes both benchmarking third party software and internal tool evaluations.
  • Provide advanced technical expertise internally and independently drive solutions across teams and departments.
  • Communicate with clients to estimate resources and timelines for custom analysis projects and then execute on the developed plan.
  • Develop programming documentation including design, requirements and instructions, as appropriate.
  • Perform and plan the development, implementation and validation of on-boarding new product technologies and applications.
  • Lead department and/or cross-functional project teams to address company initiatives.
  • Provide training and guidance to new staff.


  • Strong fundamental knowledge of Linux and bash, and efficient in working on a HPC through a terminal.
  • Strong proficiency with at least one scripting language (Python, Perl, etc.), the use of software version control and unit testing.
  • Experience with high-performance programming is a plus.
  • Readily able to discuss common packages and software within a bioinformatic workflow.
  • In-depth experience in the statistical language R and common packages.
  • Practical experience with creating experimental designs, statistical analysis plans and real-world data analysis.
  • Experience with data normalization, generalized linear models, feature and model selection, clustering techniques, dimension reduction techniques and machine learning approaches.
  • Basic knowledge of biomarker discovery and other statistical approaches of NGS data including functional enrichment and pathway analysis.
  • Strong organizational, interpersonal, leadership and communication skills.
  • Ability to effectively handle multiple tasks and projects.
  • Excellent level of accuracy and attention to detail.
  • Ability to establish and maintain effective working relationships with coworkers, managers and clients.


Bachelor's degree in computer science, bioinformatics, statistics, molecular biology, genetics or related field and 5 years relevant experience or Master’s degree in computer science, bioinformatics, statistics, molecular biology, genetics or related field and 3 years relevant experience; or PhD or educational equivalent in computer science, bioinformatics, statistics, genetics/molecular biology, or related field; or equivalent combination of education, training and experience.


  • Extensive use of keyboard requiring repetitive motion of fingers.
  • Regular sitting for extended periods of time.
  • Occasional travel (<5-10% of the time).

EEO Minorities/Females/Protected Veterans/Disabled

IQVIA is an EEO Employer - Minorities/Females/Protected Veterans/Disabled

IQVIA, Inc. provides reasonable accommodations for applicants with disabilities.  Applicants who require reasonable accommodation to submit an application for employment or otherwise participate in the application process should contact IQVIA’s Talent Acquisition team at to arrange for such an accommodation.

Job ID: R1089522